IL-12– and IL-23–induced T helper cell subsets

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IL-12– and IL-23–induced T helper cell subsets

Traditionally, CD4(+) T cells have been separated into two different subsets named T helper (Th)1 and Th2. A new IL-23-driven subset of Th cells called Th(IL-17) has now been described. The data suggest that IL-23 plays an important role in the differentiation of autoreactive pathogenic T cells. Whether these IL-23-induced Th(IL-17) cells are a unique subset or are related to other Th subsets i...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 2005

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.20042279